Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.50 |
| ▸ | RORB | Q92753 | 4/20 | 0.48 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311178 | 0.87 | CASP1 (0.48) | KMORORBRORCADORA2AADORA1 | |
| SCHEMBL31311304 | 0.84 | RORB (0.44) | KMORORBRPA1RORCADORA2A | |
| SCHEMBL31311314 | 0.84 | ABL1 (0.47) | KMORORBRORCADORA2AADORA1 | |
| SCHEMBL24508647 | 0.79 | KDM4E (0.46) | RPA1KDM4EPKM | |
| SCHEMBL13398825 | 0.77 | KDM4E (0.56) | KMORPA1ABL1CASP1NPC1 | |
| SCHEMBL24508717 | 0.77 | ALDH1A2 (0.50) | KMORORBRORCADORA2AKDM4E | |
| SCHEMBL24508613 | 0.75 | KDM4E (0.46) | KMORORBRORCNPC1RAB9A | |
| SCHEMBL13494039 | 0.75 | KMO (0.47) | KMORPA1ADORA2AADORA1ABL1 | |
| SCHEMBL6484895 | 0.74 | EGFR (0.45) | KMONPC1RAB9ACSNK2A1 | |
| SCHEMBL4373610 | 0.74 | RORB (0.46) | RORBCASP1NPC1RAB9AMARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |