Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568243 | 0.86 | MEN1 (0.41) | PTPN5L3MBTL1CA2CA1HTT | |
| SCHEMBL20635503 | 0.81 | CFTR (0.46) | L3MBTL1CYP1A2CYP2C9CYP2C19PDK1 | |
| SCHEMBL23885419 | 0.79 | CA1 (0.44) | L3MBTL1CA2CA1JAK2TP53 | |
| SCHEMBL4568023 | 0.79 | ALOX15 (0.40) | PTPN5L3MBTL1JAK2TP53MAPT | |
| SCHEMBL20051331 | 0.78 | HDAC1 (0.40) | PTPN5L3MBTL1CA2CA1JAK2 | |
| SCHEMBL23885268 | 0.78 | CA2 (0.41) | PTPN5L3MBTL1CA2CA1JAK2 | |
| SCHEMBL30254633 | 0.78 | CA2 (0.41) | PTPN5L3MBTL1CA2CA1JAK2 | |
| SCHEMBL25947062 | 0.76 | CA2 (0.39) | PTPN5L3MBTL1CA2CA1JAK2 | |
| SCHEMBL23060372 | 0.76 | PTPN5 (0.40) | PTPN5L3MBTL1CA2CA1JAK2 | |
| SCHEMBL23885564 | 0.75 | PDK1 (0.37) | PTPN5L3MBTL1CA2CA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705296-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OmniAB, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024242846-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OMNIAB, INC. (US) | 2024-11-28 | — | — | WO | disclosed |