Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313685 | 0.73 | ACHE (0.55) | BCHEACHECYP3A4LMNATP53 | |
| SCHEMBL27364151 | 0.71 | ALDH1A1 (0.43) | PTPN1BCHEACHEALDH1A1CYP3A4 | |
| SCHEMBL877438 | 0.68 | HTR2A (0.56) | BCHEACHEHTR2A | |
| SCHEMBL10488253 | 0.67 | BCHE (0.44) | BCHEACHEALDH1A1CYP3A4LMNA | |
| SCHEMBL6061696 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6061312 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL1449246 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6060774 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL6060761 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A | |
| SCHEMBL3977109 | 0.67 | HTR2A (0.54) | BCHEACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431641-B | Polyethylene resin for rotational molding and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119431641-A | Polyethylene resin for rotational molding and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-14 | — | — | CN | disclosed |