Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131388 | 1.00 | PTGES (0.56) | PTGESRXFP1AGPAT2NPC1RAB9A | |
| SCHEMBL3131878 | 0.91 | PTGES (0.69) | PTGESAGPAT2NPC1RAB9AMEN1 | |
| SCHEMBL3131870 | 0.91 | PTGES (0.69) | PTGESAGPAT2NPC1RAB9AMEN1 | |
| SCHEMBL3137146 | 0.88 | PTGES (0.58) | PTGESRXFP1AGPAT2NPC1RAB9A | |
| SCHEMBL4498498 | 0.82 | PTGES (0.81) | PTGESAGPAT2MAPTTP53SMN1; SMN2 | |
| SCHEMBL3137410 | 0.78 | PTGES (0.71) | PTGESRXFP1AGPAT2NPC1RAB9A | |
| SCHEMBL3137505 | 0.78 | MAPT (0.41) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3137503 | 0.78 | NPC1 (0.38) | RXFP1AGPAT2NPC1RAB9AMAPT | |
| SCHEMBL3137514 | 0.78 | MAPT (0.41) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3137492 | 0.78 | NPC1 (0.38) | RXFP1AGPAT2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004301-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | PTGES 162/4885RXFP1 717/4885AGPAT2 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.