Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PAH | P00439 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204413 | 0.71 | NOS1 (0.47) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL29754917 | 0.69 | NOS1 (0.54) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL31315968 | 0.67 | NOS3 (0.32) | NOS1NOS3NOS2ALDH1A1KMT2A | |
| SCHEMBL31315956 | 0.66 | PNP (0.33) | NOS1NOS3NOS2ALDH1A1KMT2A | |
| SCHEMBL31315931 | 0.65 | PNP (0.37) | GLATDP1PNPADORA2AADORA2B | |
| SCHEMBL11886629 | 0.63 | ALOX5 (0.42) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL20374994 | 0.63 | NOS1 (0.45) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL1586365 | 0.63 | PNP (0.37) | NOS1NOS3NOS2MAPTPNP | |
| SCHEMBL4649233 | 0.61 | NOS1 (0.72) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL9248337 | 0.61 | NOS1 (0.72) | NOS1NOS3NOS2USP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241548-A | Dihydropteridinone derivatives containing fused benzene rings and use thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | claimed |
| CN-119241548-A | Dihydropteridinone derivatives containing fused benzene rings and use thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | disclosed |