Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AQP1 | P29972 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316737 | 0.81 | SIRT2 (0.40) | SIRT2CNR1CNR2ABCB1SIGMAR1 | |
| SCHEMBL31316832 | 0.81 | SIRT2 (0.40) | SIRT2CNR1CNR2ABCB1SIGMAR1 | |
| SCHEMBL8210999 | 0.72 | SSTR2 (0.40) | SIRT2AQP1ABCB1SIGMAR1CA2 | |
| SCHEMBL31402347 | 0.70 | HTR1A (0.35) | MAOAMAPTCA2 | |
| SCHEMBL31316885 | 0.69 | HTR2A (0.36) | MAOACNR1AQP1MAPTABCB1 | |
| SCHEMBL11426094 | 0.69 | SIRT2 (0.46) | SIRT2MAOAMAOBABCB1 | |
| Hydrochloric Acid SCHEMBL31316984 | 0.69 | HTR2A (0.38) | MAOACA2 | |
| SCHEMBL22090769 | 0.67 | MRGPRX4 (0.38) | CNR1 | |
| SCHEMBL14367886 | 0.67 | PRKAB2 (0.40) | MAOAAQP1 | |
| SCHEMBL15758633 | 0.66 | CA2 (0.38) | AQP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |