Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16400994 | 0.89 | RAPGEF4 (0.42) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL31317204 | 0.88 | CA1 (0.40) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL31317096 | 0.86 | ALK (0.40) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL15365559 | 0.85 | RAPGEF4 (0.45) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL31317222 | 0.85 | RAPGEF4 (0.39) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL15366316 | 0.85 | BRD4 (0.40) | CA1CA2RAPGEF4HTR6ALK | |
| SCHEMBL31317223 | 0.83 | HTR6 (0.41) | RAPGEF4HTR6ALKPKMKDM4E | |
| SCHEMBL29761198 | 0.81 | HTR6 (0.37) | RAPGEF4HTR6ALKL3MBTL1PKM | |
| SCHEMBL31317265 | 0.81 | ALDH1A1 (0.41) | CA1CA2RAPGEF4HTR6PKM | |
| SCHEMBL29035513 | 0.81 | HTR6 (0.37) | RAPGEF4HTR6ALKL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739390-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | Sitala Bio Ltd (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008451-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | SITALA BIO LTD (GB) | 2025-01-09 | — | — | WO | disclosed |