Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761198 | 1.00 | HTR6 (0.37) | HTR6RAPGEF4PTGDR2VEGFAEGLN1 | |
| SCHEMBL31317239 | 0.89 | HTR6 (0.38) | HTR6RAPGEF4PTGDR2VEGFAEGLN1 | |
| SCHEMBL29761193 | 0.89 | ACHE (0.38) | HTR6RAPGEF4PTGDR2VEGFAEGLN1 | |
| SCHEMBL16400994 | 0.85 | RAPGEF4 (0.42) | HTR6RAPGEF4VEGFAEGLN1PKM | |
| SCHEMBL31317096 | 0.82 | ALK (0.40) | HTR6RAPGEF4PTGDR2VEGFAEGLN1 | |
| SCHEMBL15366122 | 0.82 | KDM4E (0.40) | HTR6RAPGEF4PKMACHEL3MBTL1 | |
| SCHEMBL31317222 | 0.81 | RAPGEF4 (0.39) | HTR6RAPGEF4VEGFAEGLN1PKM | |
| SCHEMBL15365559 | 0.81 | RAPGEF4 (0.45) | HTR6RAPGEF4VEGFAEGLN1PKM | |
| SCHEMBL15366316 | 0.81 | BRD4 (0.40) | HTR6RAPGEF4PKMALKALDH1A1 | |
| SCHEMBL31317110 | 0.81 | CA1 (0.40) | HTR6RAPGEF4VEGFAEGLN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438170-A | Nitrogen-containing bridge heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |