Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035513 | 0.89 | HTR6 (0.37) | HTR6RAPGEF4PKMACHEPTGDR2 | |
| SCHEMBL29761193 | 0.89 | ACHE (0.38) | HTR6RAPGEF4PKMACHEPTGDR2 | |
| SCHEMBL29761198 | 0.89 | HTR6 (0.37) | HTR6RAPGEF4PKMACHEPTGDR2 | |
| SCHEMBL31317194 | 0.85 | RAPGEF4 (0.42) | HTR6RAPGEF4BRD4KMT2APKM | |
| SCHEMBL16409380 | 0.85 | RAPGEF4 (0.42) | HTR6RAPGEF4BRD4KMT2APKM | |
| SCHEMBL16409381 | 0.82 | BRD4 (0.42) | HTR6RAPGEF4BRD4KMT2APKM | |
| SCHEMBL15366122 | 0.82 | KDM4E (0.40) | HTR6RAPGEF4BRD4PKMACHE | |
| SCHEMBL31317204 | 0.81 | CA1 (0.40) | HTR6RAPGEF4BRD4KMT2APKM | |
| SCHEMBL31317211 | 0.81 | RAPGEF4 (0.39) | HTR6RAPGEF4BRD4KMT2APKM | |
| SCHEMBL31317198 | 0.77 | BRD4 (0.36) | HTR6RAPGEF4BRD4KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739390-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | Sitala Bio Ltd (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008451-A1 | 2-(1H-INDOL-4-YL)METHYL)2H-INDAZOLE DERIVATIVES AS FACTOR B INHIBITORS | SITALA BIO LTD (GB) | 2025-01-09 | — | — | WO | disclosed |