Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophenytoin SCHEMBL1685397 | 0.80 | CYP2C9 (0.64) | CNR1CYP2C9CACNA1FALDH1A1MAPT | |
| SCHEMBL27224364 | 0.80 | CYP2C9 (0.64) | CNR1CYP2C9CACNA1FALDH1A1MAPT | |
| SCHEMBL10521989 | 0.74 | CYP2C9 (0.79) | CNR1CYP2C9CACNA1FALDH1A1MAPT | |
| SCHEMBL6135313 | 0.61 | LMNA (0.51) | CNR1CYP2C9CACNA1FALDH1A1MAPT | |
| SCHEMBL7537095 | 0.61 | CNR1 (0.54) | CNR1 | |
| SCHEMBL3660535 | 0.60 | CYP2C9 (0.64) | CYP2C9CACNA1FALDH1A1MAPTHTR2A | |
| SCHEMBL10521481 | 0.60 | CYP2C9 (0.64) | CYP2C9CACNA1FALDH1A1MAPTHTR2A | |
| SCHEMBL15693110 | 0.58 | TAAR1 (0.42) | CNR1ALDH1A1 | |
| SCHEMBL3412312 | 0.58 | ADAM17 (0.44) | CNR1MMP2 | |
| SCHEMBL7900340 | 0.58 | ADAM17 (0.41) | CNR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180169-B1 | 4-[4,4-bis(4-bromophenyl)-5-oxo-2-thioxoimidazolidin-1-yl]butanoic acid as an antimicrobial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12180169-B1 | 4-[4,4-bis(4-bromophenyl)-5-oxo-2-thioxoimidazolidin-1-yl]butanoic acid as an antimicrobial compound | TLR4, CASP4, IL4 | CNR1 3988/4885CYP2C9 1278/4885CACNA1F 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.