Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318507 | 0.88 | TUBB4A (0.37) | EPHX2EPHX1CYP2C9TRPM8LMNA | |
| SCHEMBL31318547 | 0.87 | SLC22A12 (0.39) | SLC22A12EPHX2EPHX1CYP2C9TRPM8 | |
| SCHEMBL31318523 | 0.82 | SLC22A12 (0.44) | SLC22A12SLC22A6SLC22A8CYP2C9MEN1 | |
| SCHEMBL31318536 | 0.80 | CYP3A4 (0.37) | EPHX2EPHX1CYP2C9MEN1LMNA | |
| SCHEMBL31318543 | 0.78 | SLC22A12 (0.65) | SLC22A12SLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL31318512 | 0.74 | SLC22A12 (0.44) | SLC22A12SLC22A6SLC22A8MEN1MAPT | |
| SCHEMBL31318521 | 0.73 | SLC22A12 (0.50) | SLC22A12SLC22A6SLC22A8CYP2C9MEN1 | |
| SCHEMBL31318529 | 0.72 | SLC22A12 (0.57) | SLC22A12SLC22A6SLC22A8CYP2C9 | |
| SCHEMBL31318496 | 0.71 | NR3C2 (0.40) | SLC22A12MEN1LMNAMAPTKMT2A | |
| SCHEMBL31318516 | 0.71 | SLC22A12 (0.43) | SLC22A12EPHX2EPHX1CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |