Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318507 | 0.88 | TUBB4A (0.37) | CYP3A4CYP2C9CYP1A2CYP2C19EPHX2 | |
| SCHEMBL31318547 | 0.88 | SLC22A12 (0.39) | CYP2C9EPHX2EPHX1HCRTR2MRGPRX4 | |
| SCHEMBL31318517 | 0.83 | SIRT3 (0.41) | CYP2C9ALDH1A1TSHRLMNAHTT | |
| SCHEMBL31318501 | 0.80 | SLC22A12 (0.41) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL31318508 | 0.80 | SLC22A12 (0.40) | CYP3A4CYP2C9EPHX2EPHX1USP2 | |
| SCHEMBL31318491 | 0.79 | TUBB4A (0.43) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL31318564 | 0.78 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL31318535 | 0.76 | SLC22A12 (0.38) | MEN1KMT2A | |
| SCHEMBL31318520 | 0.76 | MEN1 (0.36) | CYP3A4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10323544 | 0.74 | HSD17B3 (0.45) | CYP3A4CYP2C9CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |