Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318520 | 0.90 | MEN1 (0.36) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL31318492 | 0.88 | MEN1 (0.40) | ALDH1A1L3MBTL1GAAHSP90AA1SMN1; SMN2 | |
| SCHEMBL31318548 | 0.86 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1GAAHSP90AA1SMN1; SMN2 | |
| SCHEMBL31318528 | 0.83 | SLC22A6 (0.36) | ALDH1A1L3MBTL1GAAHSP90AA1SMN1; SMN2 | |
| SCHEMBL31318570 | 0.81 | PDE4B (0.39) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL31318545 | 0.81 | TUBB4A (0.39) | ALDH1A1LMNAMAPTKDM4ESLC22A12 | |
| SCHEMBL31318542 | 0.80 | SLC22A12 (0.44) | SLC22A12 | |
| SCHEMBL31318564 | 0.80 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1GAAHSP90AA1SMN1; SMN2 | |
| SCHEMBL31318525 | 0.80 | TUBB4A (0.38) | ALDH1A1L3MBTL1GAAHSP90AA1SMN1; SMN2 | |
| SCHEMBL31318517 | 0.74 | SIRT3 (0.41) | ALDH1A1L3MBTL1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |