Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318548 | 0.88 | ALDH1A1 (0.40) | ALDH1A1TPMTMAPTLMNAHPGD | |
| SCHEMBL31318577 | 0.87 | TTR (0.36) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL31318528 | 0.85 | SLC22A6 (0.36) | ALDH1A1TPMTMAPTLMNAHPGD | |
| SCHEMBL31318525 | 0.84 | TUBB4A (0.38) | ALDH1A1TPMTMAPTLMNAHPGD | |
| SCHEMBL31318550 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TPMTMAPTLMNAHPGD | |
| SCHEMBL31318536 | 0.78 | CYP3A4 (0.37) | ALDH1A1MAPTLMNAHPGDKMT2A | |
| SCHEMBL31318517 | 0.77 | SIRT3 (0.41) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL31318513 | 0.75 | MEN1 (0.42) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31318535 | 0.74 | SLC22A12 (0.38) | KMT2AMEN1RAB9A | |
| SCHEMBL31318501 | 0.74 | SLC22A12 (0.41) | ALDH1A1LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |