SCHEMBL31318705

SCHEMBL31318705

COc1ccc(C)nc1C1(C)C=CC=CN1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31290608 0.69 NOS3 (0.37)
SCHEMBL935167 0.65 CA1 (0.39) MAPT
SCHEMBL23529728 0.62
SCHEMBL7849024 0.61 KDM4E (0.53) TGFBR1MAPT
SCHEMBL7345235 0.61 ADORA1 (0.34)
SCHEMBL8285706 0.61 S1PR4 (0.50) MAPT
SCHEMBL8062500 0.60 MAPT (0.42) MAPT
SCHEMBL10304986 0.60 RAB9A (0.45) MAPT
SCHEMBL8169057 0.59 MMP2 (0.35)
SCHEMBL3075399 0.59 KDM4E (0.59) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727540-A2 FUSED BICYCLIC HETEROCYCLIC OR HETERO ARYL AMIDE COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-22 EP disclosed
WO-2024259233-A2 FUSED BICYCLIC HETEROCYCLIC OR HETERO ARYL AMIDE COMPOUNDS QUANTX BIOSCIENCES US, INC. (US) 2024-12-19 WO disclosed