Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354867 | 0.83 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL29365123 | 0.83 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL29365118 | 0.83 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL28920285 | 0.83 | HTR6 (0.44) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL21596675 | 0.82 | L3MBTL1 (0.47) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL30991290 | 0.82 | L3MBTL1 (0.47) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL16698228 | 0.82 | HTR6 (0.43) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL21596702 | 0.81 | TRPV4 (0.43) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL30991307 | 0.81 | TRPV4 (0.43) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL22864566 | 0.81 | HTR6 (0.60) | HTR6CYP3A4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |