Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 14/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596702 | 1.00 | TRPV4 (0.43) | TRPV4HTR6CYP3A4HTR2AHTR2C | |
| SCHEMBL20354867 | 0.82 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL29365118 | 0.82 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL29365123 | 0.82 | HTR6 (0.55) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL31319630 | 0.81 | HTR6 (0.41) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL21596675 | 0.81 | L3MBTL1 (0.47) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL30991290 | 0.81 | L3MBTL1 (0.47) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL28920287 | 0.80 | HTR6 (0.43) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL22864566 | 0.80 | HTR6 (0.60) | HTR6CYP3A4LMNASMN1; SMN2CYP2D6 | |
| SCHEMBL29651295 | 0.80 | HTR6 (0.60) | HTR6CYP3A4LMNASMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |