Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320134 | 0.87 | KDM4E (0.40) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL31320117 | 0.86 | KDM4E (0.39) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL28821124 | 0.81 | PSMD14 (0.43) | GAAKDM4EPOLBALDH1A1PSMD14 | |
| SCHEMBL31320123 | 0.79 | MAPK1 (0.37) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL31320125 | 0.78 | ABL1 (0.44) | ABL1 | |
| SCHEMBL31320129 | 0.77 | SMN1; SMN2 (0.52) | POLBALDH1A1ALOX15L3MBTL1KMT2A | |
| SCHEMBL31032954 | 0.77 | GAA (0.43) | GAAABL1KDM4EKMT2AMEN1 | |
| SCHEMBL31320131 | 0.77 | ABL1 (0.44) | ABL1 | |
| SCHEMBL31320132 | 0.74 | ALDH1A1 (0.51) | GAAKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL16198463 | 0.73 | KDM4E (0.46) | GAAKDM4EPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |