Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313325 | 0.84 | CYP11B2 (0.37) | ALDH1A1LMNATBXAS1PIK3CDPIK3CG | |
| SCHEMBL3126629 | 0.82 | APLNR (0.49) | TBXAS1SMN1; SMN2 | |
| SCHEMBL4304457 | 0.78 | CA2 (0.42) | TBXAS1DYRK1ACYP11B2 | |
| SCHEMBL4636652 | 0.77 | TNNI3K (0.41) | LMNAPIK3CDPIK3CGTNNI3KNAMPT | |
| SCHEMBL3465453 | 0.76 | PIK3CD (0.35) | ALDH1A1LMNAPIK3CDPIK3CGTNNI3K | |
| SCHEMBL12524821 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1LMNAPIK3CDPIK3CGTNNI3K | |
| SCHEMBL4316426 | 0.75 | PIK3CB (0.46) | ALDH1A1LMNANAMPTDYRK1ACYP11B2 | |
| SCHEMBL2433226 | 0.74 | HCAR2 (0.42) | TBXAS1NAMPTDYRK1ACYP11B2SMN1; SMN2 | |
| SCHEMBL4636646 | 0.73 | MAPT (0.43) | ALDH1A1PIK3CDPIK3CGTNNI3KMAPT | |
| SCHEMBL4311884 | 0.71 | NR3C2 (0.39) | ALDH1A1LMNAKMT2ANAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |