Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 15/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313325 | 0.86 | CYP11B2 (0.37) | APLNRTBXAS1 | |
| SCHEMBL4304457 | 0.82 | CA2 (0.42) | CA2TBXAS1 | |
| SCHEMBL3132047 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2TBXAS1 | |
| SCHEMBL24883427 | 0.76 | APLNR (0.58) | APLNRCA2CA1CA12CA9 | |
| SCHEMBL4306556 | 0.76 | KDM4E (0.45) | SMN1; SMN2 | |
| SCHEMBL2433226 | 0.76 | HCAR2 (0.42) | SMN1; SMN2TBXAS1 | |
| SCHEMBL9978250 | 0.74 | APLNR (0.55) | APLNRCA2CA1CA12CA9 | |
| SCHEMBL4316426 | 0.74 | PIK3CB (0.46) | SMN1; SMN2 | |
| SCHEMBL27940556 | 0.73 | APLNR (0.46) | APLNRCA2CA1CA12CA9 | |
| SCHEMBL24883515 | 0.73 | APLNR (0.53) | APLNRCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |