SCHEMBL31321016

SCHEMBL31321016

CO[C@@H](Cc1cccc(C)c1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.56
PPARA Q07869 12/20 0.56
SRR Q9GZT4 2/20 0.50
FFAR1 O14842 1/20 0.48
PPARD Q03181 4/20 0.48
CTBP2 P56545 1/20 0.45
POLB P06746 1/20 0.45
IDO1 P14902 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22264858 1.00 PPARG (0.56) PPARGPPARASRRFFAR1PPARD
SCHEMBL22264856 1.00 PPARG (0.56) PPARGPPARASRRFFAR1PPARD
SCHEMBL5383259 0.84 SRR (0.50) PPARGPPARASRRFFAR1PPARD
SCHEMBL9628212 0.83 SRR (0.70) PPARGPPARASRRPPARD
SCHEMBL2517934 0.83 SRR (0.70) PPARGPPARASRRPPARD
SCHEMBL16877217 0.83 SRR (0.70) PPARGPPARASRRPPARD
SCHEMBL23933859 0.83 PPARA (0.54) PPARGPPARASRRPPARD
SCHEMBL22281036 0.83 SRR (0.49) PPARGPPARASRRFFAR1PPARD
SCHEMBL757308 0.83 SRR (0.53) PPARGPPARASRRFFAR1PPARD
SCHEMBL23933856 0.83 PPARA (0.54) PPARGPPARASRRPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631168-B GPR35 modulators 普罗米修斯生物科学公司 2024-11-19 CN disclosed