Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321016 | 1.00 | PPARG (0.56) | PPARGPPARASRRFFAR1PPARD | |
| SCHEMBL22264858 | 1.00 | PPARG (0.56) | PPARGPPARASRRFFAR1PPARD | |
| SCHEMBL5383259 | 0.84 | SRR (0.50) | PPARGPPARASRRFFAR1PPARD | |
| SCHEMBL9628212 | 0.83 | SRR (0.70) | PPARGPPARASRRPPARD | |
| SCHEMBL2517934 | 0.83 | SRR (0.70) | PPARGPPARASRRPPARD | |
| SCHEMBL16877217 | 0.83 | SRR (0.70) | PPARGPPARASRRPPARD | |
| SCHEMBL23933859 | 0.83 | PPARA (0.54) | PPARGPPARASRRPPARD | |
| SCHEMBL22281036 | 0.83 | SRR (0.49) | PPARGPPARASRRFFAR1PPARD | |
| SCHEMBL757308 | 0.83 | SRR (0.53) | PPARGPPARASRRFFAR1PPARD | |
| SCHEMBL23933856 | 0.83 | PPARA (0.54) | PPARGPPARASRRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914256-B1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES INC (US) | 2024-05-29 | — | — | EP | disclosed |
| US-11773101-B2 | GPR35 modulators | PROMETHEUS BIOSCIENCES, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210380590-A1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES, INC. | 2021-12-09 | — | — | US | disclosed |
| EP-3914256-A1 | GPR35 MODULATORS | Prometheus Biosciences, Inc. (US) | 2021-12-01 | — | — | EP | disclosed |
| CN-113631168-A | GPR35 modulators | 普罗米修斯生物科学公司 | 2021-11-09 | — | — | CN | disclosed |
| US-11053251-B2 | GPR35 modulators | PROMETHEUS BIOSCIENCES, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2020154492-A1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| US-20200239476-A1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES, INC. | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380590-A1 | GPR35 MODULATORS | GPR35, GPR55, GPR65 | PPARG 34/4885PPARA 87/4885SRR 3009/4885 |
| US-11053251-B2 | GPR35 modulators | GPR35, GPR55, GPR65 | PPARG 34/4885PPARA 87/4885SRR 3009/4885 |
| US-11773101-B2 | GPR35 modulators | GPR35, GPR55, GPR65 | PPARG 34/4885PPARA 87/4885SRR 3009/4885 |
| US-20200239476-A1 | GPR35 MODULATORS | GPR35, GPR55, GPR65 | PPARG 34/4885PPARA 87/4885SRR 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.