Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322206 | 1.00 | RAPGEF3 (0.38) | RAPGEF3CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL15188819 | 0.84 | RAPGEF3 (0.44) | RAPGEF3MAPK1 | |
| SCHEMBL10445289 | 0.75 | MAPT (0.46) | CYP1A2CYP2C19GAARXFP1KCNH2 | |
| SCHEMBL6371376 | 0.73 | ALDH1A1 (0.44) | RAPGEF3 | |
| SCHEMBL25286222 | 0.72 | SMN1; SMN2 (0.36) | RAPGEF3MAPK1 | |
| SCHEMBL12467195 | 0.72 | KMT2A (0.42) | RAPGEF3MAPK1LMNA | |
| SCHEMBL31226373 | 0.71 | P2RX7 (0.46) | GAAMAPK1 | |
| SCHEMBL6370812 | 0.69 | SMN1; SMN2 (0.40) | GAAMAPK1LMNA | |
| SCHEMBL18606355 | 0.69 | L3MBTL1 (0.31) | — | |
| SCHEMBL24112995 | 0.68 | HDAC4 (0.43) | RAPGEF3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |