Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615480 | 0.93 | DRD2 (0.66) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL1765160 | 0.91 | DRD2 (0.63) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL1239489 | 0.86 | DRD2 (0.41) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| Tert-Butyl Formate SCHEMBL27677885 | 0.84 | DRD2 (0.42) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3892639 | 0.83 | DRD2 (0.54) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3892761 | 0.83 | DRD2 (0.54) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18306930 | 0.82 | OPRM1 (0.50) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6154699 | 0.82 | OPRM1 (0.50) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL654604 | 0.82 | DRD2 (0.86) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3549471 | 0.81 | DRD2 (0.52) | DRD2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |