Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1765160 | 0.98 | DRD2 (0.63) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL31322237 | 0.93 | DRD2 (0.58) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3892639 | 0.89 | DRD2 (0.54) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3892761 | 0.89 | DRD2 (0.54) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3549471 | 0.88 | DRD2 (0.52) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL2276550 | 0.86 | DRD2 (0.50) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7824744 | 0.84 | OPRM1 (0.53) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4018826 | 0.83 | DRD2 (0.44) | DRD2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL652586 | 0.81 | DRD2 (0.68) | DRD2OPRM1OPRD1SIGMAR1DRD3 | |
| Hydrochloric Acid SCHEMBL6367289 | 0.81 | DRD2 (0.42) | DRD2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11914294-B2 | Positive resist composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-02-27 | — | — | US | disclosed |
| WO-2023102022-A1 | 4-PHENYL-2-(1H-1,2,3-TRIAZOL-4-YL)PIPERIDIN-4-OL DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20220313701-A1 | MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. | 2022-10-06 | — | — | US | disclosed |
| US-20220244642-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-08-04 | — | — | US | disclosed |
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-05-12 | — | — | US | disclosed |
| CN-114341125-A | TREX1 modulators | 星座制药公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3962907-A1 | MODULATORS OF TREX1 | Constellation Pharmaceuticals, Inc. (US) | 2022-03-09 | — | — | EP | disclosed |
| US-10835520-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| WO-2020223590-A1 | MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| WO-2020186220-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2020-09-17 | — | — | WO | disclosed |
| US-4175129-A | Antiemetic 1-(benzoxazolylalkyl)-piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-11-20 | — | — | US | disclosed |
| US-4166853-A | Antihypertensive 7-trifluoromethyl-4-aminoquinolones | THE UPJOHN COMPANY (US) | 1979-09-04 | — | — | US | disclosed |
| US-4160836-A | Antiemetic 1-(benzothiazolylalkyl)piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-07-10 | — | — | US | disclosed |
| US-4126687-A | ANTIEMETIC, 1-(BENZIMIDAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-11-21 | — | — | US | disclosed |
| US-4126688-A | ANTIEMETIC 1-(BENZOTRIAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-11-21 | — | — | US | disclosed |
| US-4120969-A | ANALGETIC, ANTIDIARRHEAL ACTIVITY | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-10-17 | — | — | US | disclosed |
| US-4110333-A | ANTIEMETIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-08-29 | — | — | US | disclosed |
| US-4066772-A | ANTIEMETICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-01-03 | — | — | US | disclosed |
| US-4016281-A | Tetralone and indanone compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3951987-A | PSYCHOSEDATIVE | HOFFMANN-LA ROCHE INC. (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MMP12, SLC11A2 | DRD2 4337/4885OPRM1 2541/4885OPRD1 2755/4885 |
| US-20220313701-A1 | MODULATORS OF TREX1 | TEAD1, TREH, TSNAX | DRD2 4835/4885OPRM1 3895/4885OPRD1 3074/4885 |
| US-10835520-B2 | Phenyl derivative | S1PR2, S1PR1, S1PR3 | DRD2 1130/4885OPRM1 2400/4885OPRD1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.