Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26775415 | 1.00 | KDM4E (0.38) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL26775085 | 0.82 | KMO (0.41) | KDM4ESMN1; SMN2L3MBTL1PLCG2NPC1 | |
| SCHEMBL18171776 | 0.77 | GABRA1 (0.41) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL29640873 | 0.76 | CCR1 (0.40) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL26774950 | 0.76 | LMNA (0.41) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL26775031 | 0.73 | KDM4E (0.33) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL28934089 | 0.72 | — | — | |
| SCHEMBL30259314 | 0.72 | CTSS (0.42) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL1536559 | 0.72 | KDM4E (0.61) | KDM4ECCR1CCR5CCR8TP53 | |
| SCHEMBL30564803 | 0.70 | KDM4E (0.61) | KDM4ECCR1CCR5CCR8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119317626-A | Pyrrolidone derivatives as inhibitors of NF- κb-induced kinase | 詹森药业有限公司 | 2025-01-14 | — | — | CN | disclosed |