Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171842 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDALOX15MEN1KMT2A | |
| SCHEMBL1373138 | 0.83 | S1PR1 (0.54) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2170390 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1HPGDALOX15MEN1KMT2A | |
| SCHEMBL27923617 | 0.82 | S1PR1 (0.46) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL27923619 | 0.82 | S1PR1 (0.46) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2173707 | 0.81 | MEN1 (0.50) | ALDH1A1HPGDMEN1KMT2ATHRB | |
| SCHEMBL2169800 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15MEN1KMT2A | |
| SCHEMBL2171615 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15MEN1KMT2A | |
| SCHEMBL2185321 | 0.79 | IDO1 (0.47) | ALDH1A1HPGDALOX15MEN1KMT2A | |
| SCHEMBL2170963 | 0.77 | MEN1 (0.48) | ALDH1A1HPGDMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045580-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |