Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636639 | 0.88 | GAA (0.50) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL10867808 | 0.86 | GAA (0.43) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL10965493 | 0.80 | MAOB (0.41) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL6474768 | 0.79 | ATP4A (0.55) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL6480385 | 0.79 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| Water SCHEMBL6483418 | 0.78 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL6475062 | 0.77 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL9507972 | 0.77 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL6483278 | 0.77 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL6475609 | 0.75 | ATP4A (0.50) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060050-A | Benzimidazole compound and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |