SCHEMBL31326334

SCHEMBL31326334

N#Cc1cnc2[nH]cc(CCNCc3cccc(F)c3)c2c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 4/20 0.49
▸ SNCA P37840 2/20 0.48
▸ MPO P05164 2/20 0.46
▸ CHEK1 O14757 2/20 0.45
▸ HTR2A P28223 4/20 0.44
▸ HTR1A P08908 2/20 0.44
▸ DRD2 P14416 2/20 0.44
▸ HTR7 P34969 2/20 0.44
▸ HTR2C P28335 1/20 0.44
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ SLC6A4 P31645 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CLK1 P49759 1/20 0.42
▸ DYRK1A Q13627 1/20 0.42
▸ MET P08581 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ EGLN2 Q96KS0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL31635950 0.92 HTR6 (0.56) HTR6SNCAMPOCHEK1HTR2A
SCHEMBL31326314 0.87 HTR6 (0.55) HTR6SNCAMPOHTR2AHTR1A
SCHEMBL31326352 0.85 KMT2A (0.60) CHEK1HTR2AHTR2CCYP3A4CYP2D6
SCHEMBL31326342 0.84 HTR6 (0.52) HTR6SNCAMPOHTR2AHTR1A
SCHEMBL31326337 0.83 HTR2A (0.47) HTR6MPOCHEK1HTR2AHTR1A
Fumaric Acid SCHEMBL31635980 0.78 KMT2A (0.52) HTR6CHEK1HTR2ACYP3A4CYP2D6
SCHEMBL31326318 0.78 HTR2A (0.57) HTR6SNCAMPOHTR2AHTR1A
Fumaric Acid SCHEMBL31635996 0.77 HTR6 (0.59) HTR6SNCAMPOCHEK1HTR2A
SCHEMBL31326330 0.76 HTR2A (0.54) HTR6MPOCHEK1HTR2AHTR2C
SCHEMBL31326350 0.75 KMT2A (0.64) HTR6HTR2AHTR1ADRD2HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735441-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250361233-A1 Compounds For Activating Serotonin Receptor Psylo Pty Ltd (AU) 2025-11-27 — — US disclosed
US-12415804-B2 Compounds for activating a serotonin receptor Psylo Pty Ltd (AU) 2025-09-16 — — US disclosed
US-20250206739-A1 Compounds Psylo Pty Ltd (AU) 2025-06-26 — — US disclosed
WO-2025000051-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206739-A1 Compounds NLN, SLC18A2, PYGB HTR6 54/4885SNCA 61/4885MPO 559/4885
US-12415804-B2 Compounds for activating a serotonin receptor HTR2C, HTR6, HTR2A HTR6 2/4885SNCA 326/4885MPO 2816/4885
US-20250361233-A1 Compounds For Activating Serotonin Receptor HTR2C, HTR2A, HTR6 HTR6 3/4885SNCA 317/4885MPO 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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