Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28830016 | 0.76 | HDAC4 (0.51) | HDAC4EDNRAMAPK14BRD4PDK1 | |
| SCHEMBL9281044 | 0.75 | HDAC4 (0.54) | HDAC4EDNRABRD4PDK1KMT2A | |
| SCHEMBL704145 | 0.74 | CA4 (0.37) | ALDH1A1SMN1; SMN2L3MBTL1ESR1 | |
| SCHEMBL786747 | 0.74 | HDAC4 (0.52) | HDAC4EDNRAMAPK14BRD4PDK1 | |
| SCHEMBL21978463 | 0.74 | HPGDS (0.46) | — | |
| SCHEMBL5921550 | 0.73 | HDAC4 (0.51) | HDAC4EDNRAMAPK14BRD4PDK1 | |
| SCHEMBL31326473 | 0.72 | MAPT (0.59) | MAPK14SMOPDK1KMT2AMEN1 | |
| SCHEMBL31326494 | 0.72 | ALDH1A3 (0.34) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL21978355 | 0.72 | CYP1A2 (0.38) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27600931 | 0.72 | CA4 (0.46) | KMT2AMEN1KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |