Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713535 | 1.00 | MMP2 (0.39) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL28375120 | 0.83 | MMP2 (0.36) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL21795792 | 0.82 | MMP2 (0.35) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL28176537 | 0.80 | CYP11B1 (0.40) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL29271395 | 0.79 | NFE2L2 (0.40) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL27843286 | 0.79 | ALDH1A1 (0.45) | — | |
| SCHEMBL28825629 | 0.76 | DAO (0.41) | — | |
| SCHEMBL27801839 | 0.75 | CYP11B1 (0.36) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL28745297 | 0.73 | S100A9 (0.31) | — | |
| SCHEMBL20508396 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007863-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119241532-A | 1H-pyrazolo [4,3-c ] pyridine compound, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |