Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | TKT | P29401 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797513 | 0.79 | DAO (0.42) | DAOTRPV4KCNH2NAMPTMAP4K4 | |
| SCHEMBL13373481 | 0.79 | DAO (0.45) | DAOTRPV4KCNH2NAMPTMAP4K4 | |
| SCHEMBL17979483 | 0.79 | KIF11 (0.51) | DAOTRPV4KCNH2NAMPTMAP4K4 | |
| SCHEMBL10296101 | 0.79 | TRPV4 (0.44) | DAOTRPV4KCNH2NAMPTPPARD | |
| SCHEMBL29271395 | 0.79 | NFE2L2 (0.40) | KCNH2 | |
| SCHEMBL20508396 | 0.79 | — | — | |
| SCHEMBL24425812 | 0.78 | DAO (0.41) | DAOTRPV4KCNH2NAMPTMAP4K4 | |
| SCHEMBL12464348 | 0.77 | DAO (0.40) | DAOTRPV4KCNH2NAMPTMAP4K4 | |
| SCHEMBL23141526 | 0.77 | LOXL2 (0.53) | KCNQ2 | |
| SCHEMBL18571250 | 0.77 | DAO (0.40) | DAOTRPV4KCNH2NAMPTMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |