Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL204442 | 0.96 | TDP1 (0.77) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL6265781 | 0.96 | TDP1 (0.77) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL6397862 | 0.96 | TDP1 (0.77) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL8504999 | 0.93 | TDP1 (0.71) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL28272872 | 0.90 | TDP1 (0.67) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL8462303 | 0.90 | TDP1 (0.67) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL8592118 | 0.90 | TDP1 (0.67) | TDP1LMNAALDH1A1TSHRTHRB | |
| Glycerin SCHEMBL5583805 | 0.89 | LMNA (0.69) | TDP1LMNAALDH1A1TSHRTHRB | |
| Propylene Glycol SCHEMBL10332456 | 0.89 | TDP1 (0.91) | TDP1LMNAALDH1A1TSHRTHRB | |
| Propylene Glycol SCHEMBL3664673 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137758-A1 | Liquid Laundry Detergent Composition Comprising a Particle | THE PROCTER & GAMBLE COMPANY | 2017-05-18 | — | — | US | disclosed |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-08-05 | — | — | US | disclosed |
| CN-101500534-A | Compositions comprising betulonic acid | VALTION TEKNILLINEN (FI) | 2009-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | BET1, PGGT1B, RABGGTB | TDP1 961/4885LMNA 3692/4885ALDH1A1 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.