Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | TYMS | P04818 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329355 | 0.90 | RAB9A (0.58) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL31329352 | 0.85 | RAB9A (0.53) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL18058955 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL27915818 | 0.82 | RAB9A (0.77) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL31329346 | 0.82 | RAB9A (0.77) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL31329342 | 0.82 | RAB9A (0.71) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL31329340 | 0.82 | RAB9A (1.00) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL3593419 | 0.82 | RAB9A (1.00) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL19840422 | 0.80 | RAB9A (0.70) | SMN1; SMN2RAB9ALMNAHTTGFER | |
| SCHEMBL19029334 | 0.79 | HDAC6 (1.00) | SMN1; SMN2RAB9ALMNAHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330886-A | Benzimidazole amine derivative, preparation method thereof and beta2Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2025-01-21 | — | — | CN | disclosed |