Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329337 | 0.90 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL31329352 | 0.90 | RAB9A (0.53) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL31329342 | 0.89 | RAB9A (0.71) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL24329881 | 0.75 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL27915818 | 0.75 | RAB9A (0.77) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL31329346 | 0.75 | RAB9A (0.77) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL5984336 | 0.74 | RIPK1 (0.62) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL18058955 | 0.73 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2LMNAHTTGFER | |
| SCHEMBL2146355 | 0.72 | ALDH1A1 (0.56) | RAB9ALMNAHTTHDAC6TYMS | |
| SCHEMBL31329350 | 0.72 | RAB9A (0.71) | RAB9ASMN1; SMN2LMNAHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330886-A | Benzimidazole amine derivative, preparation method thereof and beta2Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2025-01-21 | — | — | CN | disclosed |