Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329355 | 0.90 | RAB9A (0.58) | RAB9ASMN1; SMN2LMNAGFERHTT | |
| SCHEMBL31329337 | 0.85 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2LMNAGFERHTT | |
| SCHEMBL31329338 | 0.84 | RAB9A (0.71) | RAB9ASMN1; SMN2LMNAGFERHTT | |
| SCHEMBL31329342 | 0.79 | RAB9A (0.71) | RAB9ASMN1; SMN2LMNAGFERHTT | |
| SCHEMBL18895144 | 0.73 | BRD4 (0.61) | SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL31329345 | 0.73 | NPC1 (0.74) | RAB9ASMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL5037797 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2LMNAGFERHTT | |
| SCHEMBL780389 | 0.72 | MAP4K4 (0.50) | SMN1; SMN2LMNAHTTHDAC6 | |
| SCHEMBL18895501 | 0.72 | APP (0.55) | SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL24329881 | 0.72 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2LMNAGFERHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330886-A | Benzimidazole amine derivative, preparation method thereof and beta2Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2025-01-21 | — | — | CN | disclosed |