Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM5C | P41229 | 2/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251612 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL28663446 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL2481383 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL2437939 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL9440318 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL23337477 | 0.74 | ACVRL1 (0.55) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL5906610 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL2437937 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL9440315 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTALKBH5FTO | |
| SCHEMBL3736841 | 0.73 | SMARCA2 (0.49) | KDM4EMAPTSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598190-B2 | 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| WO-2010034798-A1 | 3H-IMIDAZO [4, 5-C] PYRIDINE-6-CARBOXAMIDES AS ANTI -INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |