Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602351 | 0.75 | BRD4 (0.53) | PIK3CDPIK3CGPIK3CBCA1CA2 | |
| SCHEMBL28732947 | 0.75 | BRD4 (0.53) | PIK3CDPIK3CGPIK3CBCA1CA2 | |
| SCHEMBL22843343 | 0.74 | TEAD1 (0.48) | PIK3CDPIK3CGTEAD1YAP1CA9 | |
| SCHEMBL22718321 | 0.74 | LMNA (0.46) | TEAD1YAP1CA1CA2CA9 | |
| SCHEMBL29704124 | 0.73 | CA2 (0.51) | LRRK2CA1CA2CA9CA12 | |
| SCHEMBL22635577 | 0.73 | CYP2C9 (0.43) | PIK3CDLRRK2CA1CA2CA5A | |
| SCHEMBL22718340 | 0.72 | LRRK2 (0.40) | PIK3CDLRRK2CA1CA2CA9 | |
| SCHEMBL29704120 | 0.72 | LRRK2 (0.40) | PIK3CDLRRK2CA1CA2CA9 | |
| SCHEMBL15829876 | 0.71 | CYP1A2 (0.49) | LRRK2CYP2E1CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL24669566 | 0.70 | CA2 (0.46) | PIK3CDPIK3CGPIK3CBPIK3C3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |