Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.41 |
| ▸ | FEN1 | P39748 | 5/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29704120 | 0.87 | LRRK2 (0.40) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL22718340 | 0.87 | LRRK2 (0.40) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL31565756 | 0.79 | LMNA (0.46) | CYP2C9CYP2C19CA1CA2CA12 | |
| SCHEMBL13564332 | 0.76 | CASP6 (0.48) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL15829876 | 0.73 | CYP1A2 (0.49) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL29704124 | 0.73 | CA2 (0.51) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL31331822 | 0.73 | PIK3CD (0.43) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL16891571 | 0.72 | CYP2C19 (0.46) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL16885719 | 0.72 | CYP2C19 (0.42) | CYP2C9CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL31105631 | 0.72 | ALOX5AP (0.43) | CYP2C9ALOX5APFEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192865-B2 | Benzosulfonyl compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200354325-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192865-B2 | Benzosulfonyl compounds | YAP1, TEAD2, TEAD1 | CYP2C9 3794/4885CYP2E1 1834/4885CYP2A6 3516/4885 |
| US-20200354325-A1 | BENZOSULFONYL COMPOUNDS | YAP1, TEAD2, TEAD1 | CYP2C9 3794/4885CYP2E1 1834/4885CYP2A6 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.