Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 7/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378769 | 0.82 | TNKS2 (0.75) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL31331956 | 0.81 | AR (0.68) | AR | |
| SCHEMBL15159310 | 0.79 | AR (0.65) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL27582072 | 0.75 | KDM4E (0.48) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL14399200 | 0.74 | HPGD (0.63) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL14193711 | 0.73 | KDM4E (0.55) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL11468572 | 0.72 | LMNA (0.62) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL31331731 | 0.72 | ALDH1A1 (0.76) | KDM4EGLAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2795205 | 0.71 | KDM4E (0.67) | TNKS2KDM4EGLAGAATP53 | |
| SCHEMBL7923976 | 0.71 | KDM4E (0.53) | TNKS2KDM4EGLAGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285594-A | 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof | 浙江大学金华研究院 | 2025-01-10 | — | — | CN | disclosed |