Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718313 | 1.00 | KDM5B (0.50) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL24845157 | 0.83 | KDM5B (0.52) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL26276579 | 0.80 | KDM5B (0.50) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL24845233 | 0.80 | KDM5B (0.50) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL2968205 | 0.80 | ALDH1A1 (0.51) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL22747342 | 0.80 | KDM5B (0.47) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL22747288 | 0.78 | KDM5B (0.48) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL3672494 | 0.75 | HPGDS (0.51) | KDM5BKDM5AKDM4AKDM4CMAPT | |
| SCHEMBL18579809 | 0.75 | KDM5B (0.65) | KDM5BKDM5AKDM4AKDM4CALDH1A1 | |
| SCHEMBL9714348 | 0.74 | KDM5B (0.54) | KDM5BKDM5AKDM4AKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |