Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | VNN1 | O95497 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | BTD | P43251 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332744 | 0.86 | DGAT2 (0.48) | DGAT2HSD11B1GRIN2BGPR88 | |
| SCHEMBL31332651 | 0.86 | DGAT2 (0.48) | DGAT2HSD11B1GRIN2BGPR88 | |
| SCHEMBL31332769 | 0.82 | DGAT2 (0.41) | DGAT2HSD11B1GRIN2BGPR88 | |
| SCHEMBL31332702 | 0.82 | DGAT2 (0.41) | DGAT2HSD11B1GRIN2B | |
| SCHEMBL31332612 | 0.80 | DGAT2 (0.36) | DGAT2HSD11B1GRIN2BICMTGPR88 | |
| SCHEMBL31332724 | 0.80 | HSD11B1 (0.40) | HSD11B1GRIN2BICMT | |
| SCHEMBL31332694 | 0.79 | HSD11B1 (0.39) | DGAT2HSD11B1GRIN2BICMT | |
| SCHEMBL31332837 | 0.79 | HSD11B1 (0.39) | GRM5VNN1HSD11B1GRIN2BICMT | |
| SCHEMBL31332643 | 0.79 | HSD11B1 (0.41) | HSD11B1GRIN2BICMT | |
| SCHEMBL31332726 | 0.78 | HSD11B1 (0.38) | VNN1HSD11B1GRIN2BICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |