Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332753 | 1.00 | ICMT (0.42) | ICMTPRKACAPRKACGPRKACBHSD11B1 | |
| SCHEMBL31332690 | 0.80 | SLC6A3 (0.55) | ICMTSLC6A4SLC6A2BACE1SLC6A3 | |
| SCHEMBL31332704 | 0.80 | SLC6A3 (0.55) | ICMTSLC6A4SLC6A2BACE1SLC6A3 | |
| SCHEMBL31332698 | 0.80 | SLC6A3 (0.55) | ICMTSLC6A4SLC6A2BACE1SLC6A3 | |
| SCHEMBL31332738 | 0.79 | HSD11B1 (0.38) | ICMTPRKACAPRKACGPRKACBHSD11B1 | |
| SCHEMBL4702300 | 0.75 | SLC6A2 (0.38) | ICMTPRKACAPRKACGPRKACBHSD11B1 | |
| SCHEMBL31332798 | 0.74 | PRKACA (0.45) | ICMTPRKACAPRKACGPRKACBHSD11B1 | |
| SCHEMBL31332618 | 0.74 | SLC6A3 (0.37) | PRKACAPRKACGPRKACBSLC6A4BACE1 | |
| SCHEMBL23231697 | 0.72 | HSD11B1 (0.41) | HSD11B1SLC6A4SLC6A2BACE1ENPP2 | |
| SCHEMBL3508331 | 0.71 | ICMT (0.43) | ICMTHSD11B1SLC6A4SLC6A2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |