Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332723 | 0.82 | SLC6A4 (0.49) | HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31332763 | 0.79 | ICMT (0.42) | HSD11B1BACE1SLC6A2SLC6A4PRKACA | |
| SCHEMBL31332753 | 0.79 | ICMT (0.42) | HSD11B1BACE1SLC6A2SLC6A4PRKACA | |
| SCHEMBL31332878 | 0.73 | TSHR (0.52) | HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31332759 | 0.72 | DGAT2 (0.46) | HSD11B1MAOAMAOB | |
| SCHEMBL31332798 | 0.69 | PRKACA (0.45) | HSD11B1BACE1SLC6A2SLC6A4PRKACA | |
| SCHEMBL31332697 | 0.69 | HSD11B1 (0.40) | HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL23231697 | 0.67 | HSD11B1 (0.41) | HSD11B1BACE1SLC6A2SLC6A4 | |
| SCHEMBL612068 | 0.66 | HSD11B1 (0.42) | HSD11B1BACE1ABCC9ABCC8KCNJ11 | |
| SCHEMBL21452474 | 0.66 | ABCC9 (0.40) | HSD11B1BACE1ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |