Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.44 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.43 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332665 | 0.85 | LMNA (0.45) | LMNASIGMAR1ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL31332669 | 0.84 | LMNA (0.53) | LMNASIGMAR1ALDH1A1HSD17B2KCNQ3 | |
| SCHEMBL31332685 | 0.84 | LMNA (0.57) | LMNASIGMAR1ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL31332743 | 0.82 | LMNA (0.55) | LMNASIGMAR1ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL5675719 | 0.75 | SLC9A1 (0.51) | LMNASIGMAR1ALDH1A1DGAT2 | |
| SCHEMBL31332854 | 0.74 | SIGMAR1 (0.53) | LMNASIGMAR1ALDH1A1DGAT2MGAT2 | |
| SCHEMBL5205656 | 0.73 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1GPR88HDAC4 | |
| SCHEMBL31332788 | 0.71 | EPHX2 (0.45) | ALDH1A1MAPTTSHR | |
| SCHEMBL31332692 | 0.70 | LMNA (0.49) | LMNASIGMAR1ALDH1A1DGAT2MGAT2 | |
| SCHEMBL31332721 | 0.70 | LMNA (0.49) | LMNASIGMAR1ALDH1A1HDAC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |