Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333248 | 0.96 | MAPT (0.55) | MAPTALDH1A1LMNASIRT6THRB | |
| SCHEMBL30497525 | 0.89 | MAPT (0.53) | MAPTALDH1A1LMNASIRT6MET | |
| SCHEMBL26495618 | 0.89 | MAPT (0.53) | MAPTALDH1A1LMNASIRT6MET | |
| SCHEMBL1106913 | 0.87 | MAPT (0.68) | MAPTALDH1A1LMNASIRT6THRB | |
| SCHEMBL30307835 | 0.87 | MAPT (0.68) | MAPTALDH1A1LMNASIRT6THRB | |
| SCHEMBL31334881 | 0.87 | SIRT6 (0.48) | MAPTALDH1A1LMNASIRT6THRB | |
| SCHEMBL21786064 | 0.86 | MAPT (0.75) | MAPTALDH1A1LMNACNR1GPR119 | |
| SCHEMBL31700579 | 0.85 | MAPT (0.53) | MAPTALDH1A1LMNASIRT6MET | |
| SCHEMBL30981331 | 0.85 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAMETCNR1 | |
| SCHEMBL31333447 | 0.84 | DRD2 (0.47) | MAPTALDH1A1LMNASIRT6THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |