Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334881 | 0.86 | SIRT6 (0.48) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333435 | 0.84 | MAPT (0.55) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL31333248 | 0.83 | MAPT (0.55) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL14892233 | 0.81 | LMNA (0.53) | DRD2SIRT6MAPTSUV39H2ALDH1A1 | |
| SCHEMBL31333744 | 0.81 | SIRT6 (0.44) | SIRT6MAPTTHRBPKMALDH1A1 | |
| SCHEMBL517443 | 0.80 | ALDH1A1 (0.58) | DRD2SIRT6MAPTSUV39H2ALDH1A1 | |
| SCHEMBL381140 | 0.79 | SIRT6 (0.56) | DRD2SIRT6MAPTSUV39H2ALDH1A1 | |
| SCHEMBL31334849 | 0.79 | DRD2 (0.54) | DRD2MAPTTHRBKCNA3ALDH1A1 | |
| SCHEMBL31333982 | 0.79 | SIRT6 (0.46) | DRD2SIRT6MAPTTHRBPKM | |
| SCHEMBL14406629 | 0.78 | MAPT (0.56) | SIRT6MAPTTHRBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |