Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 11/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.46 |
| ▸ | JUN | P05412 | 5/20 | 0.46 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333366 | 0.96 | MAPK1 (0.44) | MAPK1SIGMAR1MAPK8MAPK9JUN | |
| SCHEMBL31334928 | 0.94 | SIGMAR1 (0.45) | MAPK1SIGMAR1MAPK8MAPK9JUN | |
| SCHEMBL31333436 | 0.91 | MAPK1 (0.45) | MAPK1SIGMAR1MAPK8MAPK9JUN | |
| SCHEMBL31334146 | 0.85 | MAPK8 (0.49) | MAPK1MAPK8MAPK9JUNCDK2 | |
| SCHEMBL31334411 | 0.84 | MAPK1 (0.51) | MAPK1MAPK8MAPK9JUNCDK2 | |
| SCHEMBL31333217 | 0.84 | MAPK8 (0.54) | MAPK1MAPK8MAPK9JUNCDK2 | |
| SCHEMBL31333767 | 0.82 | MAPK8 (0.50) | MAPK1MAPK8MAPK9JUNCDK2 | |
| SCHEMBL31333690 | 0.81 | CKS1B (0.51) | MAPK1 | |
| SCHEMBL31334352 | 0.81 | CKS1B (0.51) | MAPK1 | |
| SCHEMBL31333971 | 0.80 | MAPK1 (0.50) | MAPK1MAPK8MAPK9JUNCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |