Sugi Predict

Sugi Predict / Compounds / SCHEMBL31333436

SCHEMBL31333436

SCHEMBL31333436

CC(C)(C)OC(=O)NCCC(=O)N1CCC(C(=O)N2CCC(Nc3ncc(Cl)c(-c4cccc(-c5ccccc5)c4)n3)CC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 13/20 0.45
▸ MAPK8 P45983 6/20 0.44
▸ MAPK9 P45984 6/20 0.44
▸ JUN P05412 5/20 0.44
▸ CDK2 P24941 5/20 0.44
▸ MAPK10 P53779 4/20 0.44
▸ SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334928 0.96 SIGMAR1 (0.45) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31333366 0.95 MAPK1 (0.44) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31333657 0.91 MAPK1 (0.46) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31334616 0.87 MAPK8 (0.51) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31334027 0.85 MAPK1 (0.51) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31334146 0.84 MAPK8 (0.49) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31334768 0.83 MAPK1 (0.49) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31333217 0.83 MAPK8 (0.54) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31334860 0.82 MAPK1 (0.56) MAPK1MAPK8MAPK9JUNCDK2
SCHEMBL31335038 0.82 CDK2 (0.54) MAPK1MAPK8MAPK9JUNCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed