SCHEMBL31333719

SCHEMBL31333719

CC(C)(C)OC(=O)CCN1CCN(C2CCN(c3ccc(N)cc3)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL3 Q96JM7 8/20 0.41
L3MBTL1 Q9Y468 7/20 0.41
MBTD1 Q05BQ5 1/20 0.41
TP53BP1 Q12888 1/20 0.41
GPR119 Q8TDV5 4/20 0.41
ITGB3 P05106 1/20 0.40
ITGA2B P08514 1/20 0.40
HTR7 P34969 1/20 0.40
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
RAD52 P43351 1/20 0.39
GFER P55789 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334418 0.85 MAPT (0.53) MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL13313520 0.81 GPR119 (0.59) L3MBTL1GPR119MAPTGFER
SCHEMBL31333567 0.79 DDB1 (0.52)
SCHEMBL8352974 0.78 GPR119 (0.59) MEN1KMT2AL3MBTL1GPR119MAPT
SCHEMBL4821844 0.78 DRD2 (0.46) MEN1KMT2AHTR7KDM4EGAA
SCHEMBL24123667 0.77 L3MBTL3 (0.51) KMT2AL3MBTL3L3MBTL1MBTD1TP53BP1
SCHEMBL31334109 0.76 TP53 (0.39) L3MBTL3L3MBTL1KDM4ESMN1; SMN2
SCHEMBL16824829 0.76 GFER (0.53) MEN1KMT2AGPR119HTR7KDM4E
SCHEMBL31333510 0.75 CKS1B (0.48) GPR119KDM4E
SCHEMBL2880975 0.75 KMT2A (0.54) MEN1KMT2AHTR7KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed